CRSP / CRISPR Therapeutics AG / VERTEX PHARMACEUTICALS INC / MA - EXHIBIT 4 - STANDSTILL AGREEMENT. Vertex Reports Third-Quarter 2020 Financial Results -Product revenues of $1.54 billion, a 62% increase compared to Q3 2019- -Company raises revenue guidance; now expects 2020 product revenues of $6.0 to $6.2 billion- BOSTON - Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today reported consolidated financial results for the third quarter ended September 30, 2020 and revised upward its … Our Board recommends that you vote “FOR” the election of each of the nominees named in Proposal 1 of this Proxy Statement and “FOR” each of Proposals 2, 3 and 4. Whenever the Board of Directors solicits proxies with respect to the election of directors at an annual meeting of stockholders (following t, Exhibit 3.1 BY-LAWS of VERTEX PHARMACEUTICALS INCORPORATED Amended and Restated as of February 5, 2014 ARTICLE I STOCKHOLDERS Section 1. Specific voting instructions are set forth in the Proxy Statement and on both the Notice of Internet Availability of Proxy Materials and proxy card. Vertex Reports Third-Quarter 2018 Financial Results. mediainfo@vrtx.com Vertex Reports Second Quarter 2013 Financial Results and Reviews Recent Progress and Upcoming Milestones in Clinical Development Programs -Second quarter 2013 total revenues of $311 million, including net product revenues of $99 million for KALYDECO in cystic fibrosis and $156 million for INCIVEK in hepatitis C; cash position of approximately $1. At Add Files. *, Exhibit 10.35 May 18, 2012 Paul M. Silva 23 Tammer Lane Hopkinton, MA 01748 RE: Amended and Restated Change of Control Agreement Dear Paul: You are a key member of the senior management team of Vertex Pharmaceuticals Incorporated (the “Company”). 617-341-6992, Source: Vertex Pharmaceuticals Incorporated, https://www.businesswire.com/news/home/20200428006000/en/. Contact us, 13F Universe (Hedge Fund Holdings Tracker), 92532FAN0 / Vertex Pharmaceuticals Inc. CORPORATE OBLIG, Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K, Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - 8-K, Financial Statements and Exhibits, Results of Operations and Financial Condition, Submission of Matters to a Vote of Security Holders, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Triggering Events That Accelerate or Increase a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Entry into a Material Definitive Agreement, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Submission of Matters to a Vote of Security Holders, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, VRTX / Vertex Pharmaceuticals Inc. PX14A6G - -, VRTX / Vertex Pharmaceuticals Inc. PX14A6G, VRTX / Vertex Pharmaceuticals Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment, VRTX / Vertex Pharmaceuticals Inc. / FMR LLC Passive Investment, VRTX / Vertex Pharmaceuticals Inc. / BlackRock Inc. Dear Shareowners, It is a privilege to serve as your lead director Vertex Reports Second Quarter 2016 Financial Results. If you require advice in relation to any financial matter you should consult an appropriate professional. Sincerely, Darius Adamczyk Chairman and Chief Executive Officer | Notice and Proxy Statement | 2019 Vertex further announced that it will be using the “Notice and Access” method of providing proxy materials in advance of the annual meeting. Visit the link below, for archived 10-K and proxy filings. Vertex Reports Third-Quarter 2020 Financial Results, Vertex Reports Third-Quarter 2020 Financial Results -Product revenues of $1.54 billion, a 62% increase compared to Q3 2019- -Company raises revenue guidance; now expects 2020 product revenues of $6.0 to $6.2 billion- BOSTON - Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today reported consolidated financial results for the third quarter ended September 30, 2020 and revised upward its full-ye, Vertex Reports Second-Quarter 2020 Financial Results, Vertex Reports Second-Quarter 2020 Financial Results -Product revenues of $1.52 billion, a 62% increase compared to Q2 2019- -Company raises revenue guidance; now expects 2020 CF revenues of $5.7 to $5.9 billion- BOSTON - Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today reported consolidated financial results for the second quarter ended June 30, 2020 and revised upward its full-year 2020, Vertex Reports First-Quarter 2020 Financial Results, Vertex Reports First-Quarter 2020 Financial Results -Product revenues of $1.52 billion, a 77% increase compared to Q1 2019- -Company raises revenue guidance; now expects 2020 CF revenues of $5.3 to $5.6 billion- BOSTON - Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today reported consolidated financial results for the first quarter ended March 31, 2020 and revised upward its full-year 2020 f, CRSP / CRISPR Therapeutics AG / VERTEX PHARMACEUTICALS INC / MA - EXHIBIT 1. Shareholders are able to obtain the proxy statement, any amendments or supplements to the proxy statement and other documents filed by Vertex … Vertex Reports Third Quarter 2014 Financial Results. 310 (a) 11.04(a), 16.02 (b) 11.01(f), 11.04(b), 11.05(1), Exhibit 4.5 FORM OF SUBORDINATED INDENTURE VERTEX PHARMACEUTICALS INCORPORATED, ISSUER and [ ], TRUSTEE INDENTURE Dated as of [ ], 201[ ] Subordinated Debt Securities CROSS-REFERENCE TABLE(1) Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 7.09 310(b) 7.08, 7.10 310(c) Inapplicable 311(a) 7.13 311(b) 7.13 311(c) Inapplicable 312(a) 5.01, 5.02(a) 312(b) 5.02(c) 312(c), Exhibit 4.4 FORM OF SENIOR INDENTURE VERTEX PHARMACEUTICALS INCORPORATED, ISSUER and [ ], TRUSTEE INDENTURE Dated as of [ ], 201[ ] Senior Debt Securities CROSS-REFERENCE TABLE(1) Section of Trust Indenture Act Section of 1939, as amended Section of Indenture 310(a) 7.09 310(b) 7.08, 7.10 310(c) Inapplicable 311(a) 7.13 311(b) 7.13 311(c) Inapplicable 312(a) 5.01, 5.02(a) 312(b) 5.02(c) 312(c) 5.0. 617.341.6100 July 24, 2019 Reshma Kewalramani 174 Winding River Road Wellesley, MA 02482 RE: Change of Control Agreement Dear Reshma: You are a key member of the senior management team of Vertex Pharmaceuticals Incorporated (the “Company”). Vertex Reports Full-Year and Fourth Quarter 2014 Financial Results and Provides Guidance for 2015 -Full-year 2014 total revenues of $580 million, including net product revenues of $464 million for KALYDECO in cystic fibrosis- -Cash, cash equivalents and marketable securities of approximately $1. Shareholders are able to obtain the proxy statement, any amendments or supplements to the proxy statement and other documents filed by Vertex with the Securities and Exchange Commission for no charge by visiting www.sec.gov. This summary does not contain all of the information Exhibit Vertex to Acquire CTP-656 from Concert Pharmaceuticals for the Treatment of Cystic Fibrosis -Vertex to develop CTP-656 for potential use in future combination regimens aimed at treating the underlying cause of CF- -Concert to receive $160 million in cash with potential for $90 million in future regulatory approval milestone payments- BOSTON, March 6, 2017 ? (ivacaftor) in cystic fibrosis- -Vertex increases guidance for 2015 KALYDECO net revenues; now expects KALYDECO revenues of $605 to $620 million- BOSTON - Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today reported consolidated financial results for the quarter ended September 30, 2015 . 2020 Proxy Statement 3 DRIVING OPERATIONAL EXCELLENCE We continue to improve execution in our factories and across our supply chain, driving out unnecessary costs and improving our customer service. Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced that it has signed a definitive asset purchase agreement to acquire CTP-656 from Concert Pharmaceuticals (Nasdaq: CNCE). You should read the entire proxy statement carefully before voting. reports on a regular basis. Notice of Annual Meeting of Stockholders How to Vote Your vote is important to the future of CVS Health. 2019 Proxy Statement: Add Files. 2016 Proxy Statement 2.3 MB. The Investor Relations website contains information about Vertex Pharmaceuticals's business for stockholders, potential investors, and financial analysts. 2018 Proxy Statement. Fintel makes no representations or warranties in relation to this website or the information and materials provided on this website. This summary does not contain all the information that you should consider, and you should carefully read the entire proxy statement and our fiscal 2019 Annual Report to Shareholders before voting. Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced that, due to public health and travel safety concerns related to the ongoing COVID-19 pandemic, its 2020 Annual Meeting of Shareholders will be held as a virtual meeting. Agreement ?) Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston, MA 02210-1862 Tel: 617-341-6100 www. Appendix A – Vertex Energy, Inc. 2019 Equity Incentive Plan. Documents; Add Files. 2020. 2017 Proxy Statement: Add Files. 2019-05-06 sec.gov PROXY MEMORANDUM To: Vertex Pharmaceutical Shareholders Subject: Shareholder resolution on extent to which risks related to public concern over drug pricing are integrated into incentive compensation policies for senior executives Date: May 6, 2019 Contact: Catherine Rowan, Director, Socially Responsible Investments, Trinity Health 2019 Proxy Statement 8.2 MB. Two Phase 3 Studies of the Tezacaftor/Ivacaftor Combination Treatment Met Primary Endpoints with Statistically Significant Improvements in Lung Function (FEV 1 ) in People with Cystic Fibrosis. The chart on this page features a breakdown of the total annual pay for Terrence C. Kearney at VERTEX PHARMACEUTICALS INC / MA as reported in their proxy statements.. Fees Earned or Paid in Cash: This is the amount of fixed retainers and meeting fees and paid in the form of cash. WHE, Employment Agreement, dated as of July 24, 2019, between Vertex Pharmaceuticals Incorporated and Reshma Kewalramani. Vertex Reports Second-Quarter 2017 Financial Results. Vertex Reports First-Quarter 2019 Financial Results - First-quarter 2019 product revenues of $857 million, a 34% increase compared to $638 million in 2018- - First-quarter 2019 GAAP operating income increased 115% to $277 million; non-GAAP operating income increased 81% to $377 million - - On track to choose best triple combination regimen in Q2 2019; NDA submission planned for Q3 2019 - BOSTON - Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today reported consolidated financial results for the first quarter ended March 31, 2019 and reiterated full-year 2019 financial guidance. Execution Copy AMENDMENT NO. Exhibit Vertex Reports First-Quarter 2017 Financial Results - First-quarter 2017 cystic fibrosis product revenues of $481 million ; $295 million for ORKAMBI and $186 million for KALYDECO- -Company reiterates 2017 guidance for ORKAMBI product revenues of $1. 2017 Proxy Statement 2.5 MB. and the other lenders party thereto. Exhibit Vertex Pharmaceuticals Incorporated Page 1 of 1 Vertex Provides Update on Business and Financial Performance and Research and Development Programs -Full-year 2016 product revenues of approximately $703 million for KALYDECO and $979 million for ORKAMBI; total 2016 CF product revenues of $1. Vertex Reports First Quarter 2014 Financial Results and Provides Updates on Key Business Priorities -Net product revenues of $100 million for KALYDECO in cystic fibrosis- -Cash, cash equivalents and marketable securities of $1. JOINT DEVELOPMENT AND COMMERCIALIZATION AGREEMENT BETWEEN VERTEX PHARMACEUTICALS INCORPORATED VERTEX PHARMACEUTICALS (EUROPE) LIMITED AND CRISPR THERAPEUTICS AG CRISPR THERAPEUTICS LIM, Vertex Pharmaceuticals Non-Employee Board Compensation. 2014 Proxy Statement. © 2015-2020 Fintel Ventures LLC. Vertex Reports First Quarter 2016 Financial Results. 2018 Proxy Statement 1.1 MB. and reports related to the specific securities sold, such as registration statements (S-1, S-8) and prospectus (FWP). Unaudited pro forma consolidated financial information, Exhibit Exhibit 99.1 Unaudited pro forma consolidated financial information On October 23, 2017, Vertex Pharmaceuticals Incorporated (?Vertex? “FOR” 3. 2016 Proxy Statement 2.5 MB. 2016 Proxy Statement: Add Files. Vertex Reports Full-Year and Fourth-Quarter 2016 Financial Results. This proxy statement and the enclosed proxy card are first being mailed or furnished to our shareholders on or about April 29, 2019. 2019 Proxy Statement. The Notice of Internet Availability of Proxy Materials contains instructions on how to access the Company’s proxy materials online, including its proxy statement and Annual Report on Form 10-K for the year ended December 31, 2019, as well as instructions on how shareholders may vote their shares at the Annual Meeting. Improve your mastery of Fintel and investing by attending a webinar.
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